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KMID : 0384119860060010131
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Korean Journal of Clinical Pathology
1986 Volume.6 No. 1 p.131 ~ p.135
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Three Cases of Evans Syndrome
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Abstract
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Evans syndrome is a combination of acquired autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura in children and adults, the criteria of a diagnosis of Evans syndrome are 1) hemolytic anemia with a positive direct Coombs´ test and thrombocytopenia occurring either simultaneously or in succession and 2) the absence of any known underlying etiology.
We had encountered three cases of Evans syndrome in a 21 year-old, a 34 yearold and a 25 year-old female patients whose chief complaints were excessive vaginal bleeding, headache and dizziness.
On the peripheral blood examination, severe anemia and thrombocytopenia were revealed. The bone marrow was moderate to severe hypercellular with erythroid hyperplasia and megakaryocytic proliferation. Coombs´ test by polyvalent antiglobulin and antiplatelet antibody test by platelet factor 3 assay were positive.
All three patients were improved during steroid therapy. Continuous follow-up examination and treatment could not be done because of economic problems.
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